B6 Resins for Oligonucleotide Synthesis
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
N 30 000 |
TentaGel® N OH |
90 µm |
200 - 250 µmol/g |
1g |
|
N 30 000 |
TentaGel® N OH |
90 µm |
200 - 250 µmol/g |
5g |
|
N 30 000 |
TentaGel® N OH |
90 µm |
200 - 250 µmol/g |
25g |
|
N 30 002 |
TentaGel® N NH? |
90 µm |
200 - 250 µmol/g |
1g |
|
N 30 002 |
TentaGel® N NH? |
90 µm |
200 - 250 µmol/g |
5g |
|
N 30 002 |
TentaGel® N NH? |
90 µm |
200 - 250 µmol/g |
25g |
B6.2
Preloaded TentaGel® N Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
N 30 002-1 |
TentaGel® N A |
90 µm |
170 - 220 µmol/g |
1g |
|
N 30 002-1 |
TentaGel® N A |
90 µm |
170 - 220 µmol/g |
5g |
|
N 30 002-1 |
TentaGel® N A |
90 µm |
170 - 220 µmol/g |
25g |
|
N 30 002-2 |
TentaGel® N C |
90 µm |
170 - 220 µmol/g |
1g |
|
N 30 002-2 |
TentaGel® N C |
90 µm |
170 - 220 µmol/g |
5g |
|
N 30 002-2 |
TentaGel® N C |
90 µm |
170 - 220 µmol/g |
25g |
|
N 30 002-3 |
TentaGel® N G |
90 µm |
170 - 220 µmol/g |
1g |
|
N 30 002-3 |
TentaGel® N G |
90 µm |
170 - 220 µmol/g |
5g |
|
N 30 002-3 |
TentaGel® N G |
90 µm |
170 - 220 µmol/g |
25g |
|
N 30 002-4 |
TentaGel® N T |
90 µm |
170 - 220 µmol/g |
1g |
|
N 30 002-4 |
TentaGel® N T |
90 µm |
170 - 220 µmol/g |
5g |
|
N 30 002-4 |
TentaGel® N T |
90 µm |
170 - 220 µmol/g |
25g |
B7.1.1
HypoGel® Bromo Acetal Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 17
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
5g |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
25g |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
100g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
B7.1.2
TentaGel® Bromo Acetal Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 47; see also: General Information
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
5g |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
25g |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
100g |
B7.2.1
HypoGel® Diol Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
5g |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
25g |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
100g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
5g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
25g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
100g |
B7.2.2
TentaGel® Diol Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 010 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
5g |
|
HL 12 010 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
25g |
|
HL 12 010 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
100g |
B7.3.1
p - Nitrophenyl Carbonate on TentaGel PHB Resin
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates.
Literature
L 4, L 5, L 6, L 7, L 8, L 24, L 25, L 43, L 54; see also: General Information.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 050 |
TentaGel® S – NPC |
90 µm |
0.2 - 0.3 mmol/g |
1g |
|
S 30 050 |
TentaGel® S – NPC |
90 µm |
0.2 - 0.3 mmol/g |
5g |
|
S 30 050 |
TentaGel® S - NPC |
90 µm |
0.2 - 0.3 mmol/g |
25g |
B7.3.2
p - Nitrophenyl Carbonate on Wang Resin
Amines can be attached to the p-nitrophenyl carbonate resin to form the corresponding resin bound carbamates. As an example the following compounds were synthesized by modifications on the resin bound carbamates: unsymetrical diamines, allylamines, guanidines, hydantoines, piperazines, triazolidienones, quinazoline diones ect.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 50 |
Polystyrene Wang NPC |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
1g |
|
H 100 50 |
Polystyrene Wang NPC |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 100 50 |
Polystyrene Wang NPC |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
25g |
|
H 400 50 |
Polystyrene Wang NPC |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
1g |
|
H 400 50 |
Polystyrene Wang NPC |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 400 50 |
Polystyrene Wang NPC |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
25g |
These resins with the immobilized acrylic acid are supports for the SOPS of tertiary amines. The first step is a Michael addition of a primary or secondary amine followed by quarternization with the appropriate alkyl halide. b-Elimination yields the tertiary amine.
Literature
L 43
Please select a subcategory:
B7.4.1
Acrylic Ester attached to Polar PEG Spacer Resins
HypoGel® REM Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200110150 180 |
HypoGel® 200 REM |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP200110150 180 |
HypoGel® 200 REM |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP200110150 180 |
HypoGel® 200 REM |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
|
SP400110150 180 |
HypoGel® 400 REM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
5g |
|
SP400110150 180 |
HypoGel® 400 REM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
25g |
|
SP400110150 180 |
HypoGel® 400 REM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
100g |
TentaGel® REM Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 018 |
TentaGel® HL REM |
75 µm |
0.3 - 0.5 mmol/g |
5g |
|
HL 12 018 |
TentaGel® HL REM |
75 µm |
0.3 - 0.5 mmol/g |
25g |
|
HL 12 018 |
TentaGel® HL REM |
75 µm |
0.3 - 0.5 mmol/g |
100g |
B7.4.2
Polystyrene REM Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 18 |
Polystyrene A REM |
100 - 200 mesh |
0.8 - 1.3 mmol/g |
5g |
|
HA 1 100 18 |
Polystyrene A REM |
100 - 200 mesh |
0.8 - 1.3 mmol/g |
25g |
|
HA 1 100 18 |
Polystyrene A REM |
100 - 200 mesh |
0.8 - 1.3 mmol/g |
100g |
|
HA 1 400 18 |
Polystyrene A REM |
200 - 400 mesh |
0.8 - 1.3 mmol/g |
5g |
|
HA 1 400 18 |
Polystyrene A REM |
200 - 400 mesh |
0.8 - 1.3 mmol/g |
25g |
|
HA 1 400 18 |
Polystyrene A REM |
200 - 400 mesh |
0.8 - 1.3 mmol/g |
100g |
|
HA 125160 18 |
Polystyrene A REM |
125 - 160 µm |
0.8 - 1.3 mmol/g |
5g |
|
HA 125160 18 |
Polystyrene A REM |
125 - 160 µm |
0.8 - 1.3 mmol/g |
25g |
|
HA 125160 18 |
Polystyrene A REM |
125 - 160 µm |
0.8 - 1.3 mmol/g |
100g |
|
HA 160200 18 |
Polystyrene A REM |
160 - 200 µm |
0.8 - 1.0 mmol/g |
5g |
|
HA 160200 18 |
Polystyrene A REM |
160 - 200 µm |
0.8 - 1.0 mmol/g |
25g |
|
HA 160200 18 |
Polystyrene A REM |
160 - 200 µm |
0.8 - 1.0 mmol/g |
100g |
|
HA 250315 18 |
Polystyrene A REM |
250 - 315 µm |
0.7 - 1.0 mmol/g |
5g |
|
HA 250315 18 |
Polystyrene A REM |
250 - 315 µm |
0.7 - 1.0 mmol/g |
25g |
|
HA 250315 18 |
Polystyrene A REM |
250 - 315 µm |
0.7 - 1.0 mmol/g |
100g |
|
HA 400450 18 |
Polystyrene A REM |
400 - 450 µm |
0.7 - 1.0 mmol/g |
5g |
|
HA 400450 18 |
Polystyrene A REM |
400 - 450 µm |
0.7 - 1.0 mmol/g |
25g |
|
HA 400450 18 |
Polystyrene A REM |
400 - 450 µm |
0.7 - 1.0 mmol/g |
100g |
|
HA 500560 18 |
Polystyrene A REM |
500 - 560 µm |
0.7 - 1.0 mmol/g |
5g |
|
HA 500560 18 |
Polystyrene A REM |
500 - 560 µm |
0.7 - 1.0 mmol/g |
25g |
|
HA 500560 18 |
Polystyrene A REM |
500 - 560 µm |
0.7 - 1.0 mmol/g |
100g |
B7.5.1
Resins for Amine and Amide Terminated Compounds
B7.5.1.1
Rink-Amide Linker on Aminoethyl Polystyrene Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 23 |
Polystyrene A RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
5g |
|
HA 1 100 23 |
Polystyrene A RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
25g |
|
HA 1 100 23 |
Polystyrene A RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
100g |
|
HA 1 400 23 |
Polystyrene A RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
5g |
|
HA 1 400 23 |
Polystyrene A RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
25g |
|
HA 1 400 23 |
Polystyrene A RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
100g |
|
HA 125160 23 |
Polystyrene A RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
5g |
|
HA 125160 23 |
Polystyrene A RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
25g |
|
HA 125160 23 |
Polystyrene A RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
100g |
|
HA 160200 23 |
Polystyrene A RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
5g |
|
HA 160200 23 |
Polystyrene A RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
25g |
|
HA 160200 23 |
Polystyrene A RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
100g |
|
HA 250315 23 |
Polystyrene A RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
5g |
|
HA 250315 23 |
Polystyrene A RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
25g |
|
HA 250315 23 |
Polystyrene A RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
100g |
|
HA 400450 23 |
Polystyrene A RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
5g |
|
HA 400450 23 |
Polystyrene A RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
25g |
|
HA 400450 23 |
Polystyrene A RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
100g |
|
HA 500560 23 |
Polystyrene A RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
5g |
|
HA 500560 23 |
Polystyrene A RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
25g |
|
HA 500560 23 |
Polystyrene A RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
100g |
B7.5.1.2
Rink-Amide Linker on Aminomethyl Polystyrene Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 23 |
Polystyrene AM RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
5g |
|
H 100 23 |
Polystyrene AM RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
25g |
|
H 100 23 |
Polystyrene AM RAM |
100 - 200 mesh |
0.6 - 0.8 mmol/g |
100g |
|
H 400 23 |
Polystyrene AM RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
5g |
|
H 400 23 |
Polystyrene AM RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
25g |
|
H 400 23 |
Polystyrene AM RAM |
200 - 400 mesh |
0.6 - 0.8 mmol/g |
100g |
|
H 125160 23 |
Polystyrene AM RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
5g |
|
H 125160 23 |
Polystyrene AM RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
25g |
|
H 125160 23 |
Polystyrene AM RAM |
125 - 160 µm |
0.4 - 0.7 mmol/g |
100g |
|
H 160200 23 |
Polystyrene AM RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
5g |
|
H 160200 23 |
Polystyrene AM RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
25g |
|
H 160200 23 |
Polystyrene AM RAM |
160 - 200 µm |
0.4 - 0.7 mmol/g |
100g |
|
H 250315 23 |
Polystyrene AM RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
5g |
|
H 250315 23 |
Polystyrene AM RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
25g |
|
H 250315 23 |
Polystyrene AM RAM |
250 - 315 µm |
0.4 - 0.7 mmol/g |
100g |
|
H 400450 23 |
Polystyrene AM RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
5g |
|
H 400450 23 |
Polystyrene AM RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
25g |
|
H 400450 23 |
Polystyrene AM RAM |
400 - 450 µm |
0.4 - 0.7 mmol/g |
100g |
|
H 500560 23 |
Polystyrene AM RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
5g |
|
H 500560 23 |
Polystyrene AM RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
25g |
|
H 500560 23 |
Polystyrene AM RAM |
500 - 560 µm |
0.4 - 0.7 mmol/g |
100g |
B7.5.1.3
Rink-Amide Linker on HypoGel® Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 230 |
HypoGel® 200 RAM |
110 - 150 µm |
0.6 - 0.7 mmol/g |
5g |
|
SP200 110150 230 |
HypoGel® 200 RAM |
110 - 150 µm |
0.6 - 0.7 mmol/g |
25g |
|
SP200 110150 230 |
HypoGel® 200 RAM |
110 - 150 µm |
0.6 - 0.7 mmol/g |
100g |
|
SP400 110150 230 |
HypoGel® 400 RAM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
5g |
|
SP400 110150 230 |
HypoGel® 400 RAM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
25g |
|
SP400 110150 230 |
HypoGel® 400 RAM |
110 - 150 µm |
0.5 - 0.6 mmol/g |
100g |
B7.5.1.4
Rink-Amide Linker on TentaGel® Resins
B7.5.1.4.1
TentaGel® HL RAM RAM Linker Attached to High Loaded TentaGel Resins
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 023 |
TentaGel® HL RAM |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL 12 023 |
TentaGel® HL RAM |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL 12 023 |
TentaGel® HL RAM |
75 µm |
0.3 - 0.4 mmol/g |
25g |
|
HL 12 023 |
TentaGel® HL RAM |
75 µm |
0.3 - 0.4 mmol/g |
100g |
B7.5.1.4.2
TentaGel® MB RAM RAM Linker Attached to TentaGel Macrobeads
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95 % TFA.
Literature
L 3
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 230 |
TentaGel® MB RAM |
140 - 170 µm |
0.3 - 0.4 mmol/g |
1g |
|
MB 160 230 |
TentaGel® MB RAM |
140 - 170 µm |
0.3 - 0.4 mmol/g |
5g |
|
MB 160 230 |
TentaGel® MB RAM |
140 - 170 µm |
0.3 - 0.4 mmol/g |
25g |
|
MB 160 230 |
TentaGel® MB RAM |
140 - 170 µm |
0.3 - 0.4 mmol/g |
100g |
|
MB 250 230 |
TentaGel® MB RAM |
200 - 250 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 230 |
TentaGel® MB RAM |
200 - 250 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 250 230 |
TentaGel® MB RAM |
200 - 250 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 250 230 |
TentaGel® MB RAM |
200 - 250 µm |
0.2 - 0.3 mmol/g |
100g |
|
MB 250 230 |
TentaGel® MB RAM |
280 - 320 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 230 |
TentaGel® MB RAM |
280 - 320 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 300 230 |
TentaGel® MB RAM |
280 - 320 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 300 230 |
TentaGel® MB RAM |
280 - 320 µm |
0.2 - 0.3 mmol/g |
100g |
B7.5.1.4.3
TentaGel® R RAM RAM Linker Attached to TentaGel Research Resins
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
TentaGel® R represents a special designed resin for research synthesis. Long peptide sequences (up to 100 residues) and difficult sequences are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; ee also: General Information
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
R 28 023 |
TentaGel® R RAM |
90 µm |
0.18 - 0.22 mmol/g |
1g |
|
R 28 023 |
TentaGel® R RAM |
90 µm |
0.18 - 0.22 mmol/g |
5g |
|
R 28 023 |
TentaGel® R RAM |
90 µm |
0.18 - 0.22 mmol/g |
25g |
|
R 28 023 |
TentaGel® R RAM |
90 µm |
0.18 - 0.22 mmol/g |
50g |
B7.5.1.4.4
TentaGel® S RAM RAM Linker Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptide amides up to 40 residues in length.
This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved by 95 % TFA.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 023 |
TentaGel® S RAM |
90 µm |
0.2 - 0.27 mmol/g |
1g |
|
S 30 023 |
TentaGel® S RAM |
90 µm |
0.2 - 0.27 mmol/g |
5g |
|
S 30 023 |
TentaGel® S RAM |
90 µm |
0.2 - 0.27 mmol/g |
25g |
|
S 30 023 |
TentaGel® S RAM |
90 µm |
0.2 - 0.27 mmol/g |
100g |
B7.5.2
Resins for Carboxy Terminated Compounds
B7.5.2.1
3-Methoxy-4-(Hydroxymethyl) Phenoxyacetic Acid Based Resins (AC-Linker) on TentaGel®
B7.5.2.1.1
TentaGel® HL AC AC Linker on High Loaded TentaGel Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 011 |
TentaGel® HL AC |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL 12 011 |
TentaGel® HL AC |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL 12 011 |
TentaGel® HL AC |
75 µm |
0.3 - 0.4 mmol/g |
25g |
|
HL 12 011 |
TentaGel® HL AC |
75 µm |
0.3 - 0.4 mmol/g |
50g |
B7.5.2.1.2
TentaGel® MB AC AC Linker on TentaGel Macrobead Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 110 |
TentaGel® MB AC |
140 - 170 µm |
0.4 - 0.6 mmol/g |
1g |
|
MB 160 110 |
TentaGel® MB AC |
140 - 170 µm |
0.4 - 0.6 mmol/g |
5g |
|
MB 160 110 |
TentaGel® MB AC |
140 - 170 µm |
0.4 - 0.6 mmol/g |
25g |
|
MB 160 110 |
TentaGel® MB AC |
140 - 170 µm |
0.4 - 0.6 mmol/g |
50g |
|
MB 250 110 |
TentaGel® MB AC |
200 - 250 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 110 |
TentaGel® MB AC |
200 - 250 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 250 110 |
TentaGel® MB AC |
200 - 250 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 250 110 |
TentaGel® MB AC |
200 - 250 µm |
0.2 - 0.3 mmol/g |
50g |
|
MB 300 110 |
TentaGel® MB AC |
280 - 320 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 300 110 |
TentaGel® MB AC |
280 - 320 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 300 110 |
TentaGel® MB AC |
280 - 320 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 300 110 |
TentaGel® MB AC |
280 - 320 µm |
0.2 - 0.3 mmol/g |
50g |
B7.5.2.1.3
TentaGel® S AC AC Linker on Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems.
Esters can be cleaved by 1-5% TFA in CH?Cl?.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 011 |
TentaGel® S AC |
90 µm |
0.2 - 0.3 mmol/g |
1g |
|
S 30 011 |
TentaGel® S AC |
90 µm |
0.2 - 0.3 mmol/g |
5g |
|
S 30 011 |
TentaGel® S AC |
90 µm |
0.2 - 0.3 mmol/g |
25g |
|
S 30 011 |
TentaGel® S AC |
90 µm |
0.2 - 0.3 mmol/g |
50g |
B7.5.2.2
HMPA Polystyrene Resins
B7.5.2.2.1
4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminoethyl Polystyrene Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 15 |
Polystyrene A HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
5g |
|
HA 1 100 15 |
Polystyrene A HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
25g |
|
HA 1 100 15 |
Polystyrene A HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
100g |
|
HA 1 400 15 |
Polystyrene A HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
5g |
|
HA 1 400 15 |
Polystyrene A HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
25g |
|
HA 1 400 15 |
Polystyrene A HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
100g |
|
HA 125160 15 |
Polystyrene A HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
HA 125160 15 |
Polystyrene A HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
HA 125160 15 |
Polystyrene A HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
|
HA 160200 15 |
Polystyrene A HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
5g |
|
HA 160200 15 |
Polystyrene A HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
25g |
|
HA 160200 15 |
Polystyrene A HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
100g |
|
HA 250315 15 |
Polystyrene A HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 250315 15 |
Polystyrene A HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 250315 15 |
Polystyrene A HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
HA 400450 15 |
Polystyrene A HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 400450 15 |
Polystyrene A HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 400450 15 |
Polystyrene A HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
HA 500560 15 |
Polystyrene A HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 500560 15 |
Polystyrene A HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 500560 15 |
Polystyrene A HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.5.2.2.2
4-(Hydroxymethyl) Phenoxyacetic Acid (HMPA) on Aminomethyl Polystyrene Resins
This resin is derivatized from aminomethyl polystyrene by coupling with the TFA-labile 4-(hydroxymethyl)-phenoxyacetic acid linker and is an alternative to the PHB resins.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 15 |
Polystyrene AM HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 100 15 |
Polystyrene AM HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
25g |
|
H 100 15 |
Polystyrene AM HMPA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
100g |
|
H 400 15 |
Polystyrene AM HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 400 15 |
Polystyrene AM HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
25g |
|
H 400 15 |
Polystyrene AM HMPA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
100g |
|
H 125160 15 |
Polystyrene AM HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
H 125160 15 |
Polystyrene AM HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
H 125160 15 |
Polystyrene AM HMPA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
|
H 160200 15 |
Polystyrene AM HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
5g |
|
H 160200 15 |
Polystyrene AM HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
25g |
|
H 160200 15 |
Polystyrene AM HMPA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
100g |
|
H 250315 15 |
Polystyrene AM HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 250315 15 |
Polystyrene AM HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 250315 15 |
Polystyrene AM HMPA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 400450 15 |
Polystyrene AM HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 400450 15 |
Polystyrene AM HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 400450 15 |
Polystyrene AM HMPA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 500560 15 |
Polystyrene AM HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 500560 15 |
Polystyrene AM HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 500560 15 |
Polystyrene AM HMPA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.5.2.3
Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) attached to TentaGel® Resins
B7.5.2.3.1
TentaGel® HL PHB PHB Attached to High Loaded TentaGel Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL12 013 |
TentaGel® HL PHB |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL12 013 |
TentaGel® HL PHB |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL12 013 |
TentaGel® HL PHB |
75 µm |
0.3 - 0.4 mmol/g |
25g |
B7.5.2.3.2
TentaGel® MB PHB PHB Attached to TentaGel Macrobead Resins
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 130 |
TentaGel® MB PHB |
140 - 170 µm |
0.3 - 0.5 mmol/g |
1g |
|
MB 160 130 |
TentaGel® MB PHB |
140 - 170 µm |
0.3 - 0.5 mmol/g |
5g |
|
MB 160 130 |
TentaGel® MB PHB |
140 - 170 µm |
0.3 - 0.5 mmol/g |
25g |
|
MB 250 130 |
TentaGel® MB PHB |
200 - 250 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 130 |
TentaGel® MB PHB |
200 - 250 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 250 130 |
TentaGel® MB PHB |
200 - 250 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 300 130 |
TentaGel® MB PHB |
280 - 320 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 300 130 |
TentaGel® MB PHB |
280 - 320 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 300 130 |
TentaGel® MB PHB |
280 - 320 µm |
0.2 - 0.3 mmol/g |
25g |
B7.5.2.3.3
TentaGel® R PHB PHB Attached to TentaGel Research Resins
A special designed resin for research synthesis. Long peptide sequences (up to 100 residues), difficult sequences and PNA´s are synthesized on this support. The resin shows an increased swelling volume and a significant lower loading.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
R 28 013 |
TentaGel® R PHB |
90 µm |
0.18 - 0.23 mmol/g |
1g |
|
R 28 013 |
TentaGel® R PHB |
90 µm |
0.18 - 0.23 mmol/g |
5g |
|
R 28 013 |
TentaGel® R PHB |
90 µm |
0.18 - 0.23 mmol/g |
25g |
|
R 28 013 |
TentaGel® R PHB |
90 µm |
0.18 - 0.23 mmol/g |
50g |
B7.5.2.3.4
TentaGel® S PHB PHB Attached to Standard TentaGel Resins
Standard resin for a large number of applications, useful in batch and flow through systems. This resin is recommended for synthesis of standard peptides up to 40 residues in length.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 013 |
TentaGel® S PHB |
90 µm |
0.2 - 0.3 mmol/g |
1g |
|
S 30 013 |
TentaGel® S PHB |
90 µm |
0.2 - 0.3 mmol/g |
5g |
|
S 30 013 |
TentaGel® S PHB |
90 µm |
0.2 - 0.3 mmol/g |
25g |
|
S 30 013 |
TentaGel® S PHB |
90 µm |
0.2 - 0.3 mmol/g |
100g |
B7.5.2.4
Para Hydroxybenzyl Alcohol ( PHB, Wang Linker) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high capacities and a hydrophilicity between polystyrene and TentaGel®
The parahydroxybencyl alcohol attached to TentaGel make this resin ideal for attaching carboxylic acids for further functionalisation and peptide synthesis. Cleavage conditions are concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids, peptides or cyclization-cleavage under acidic or basic conditions. This resin is recommended for the synthesis of short peptides (10 - 15 residues).
Literature
L 17
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 130 |
HypoGel® 200 PHB |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP200 110150 130 |
HypoGel® 200 PHB |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP200 110150 130 |
HypoGel® 200 PHB |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
|
SP400 110150 130 |
HypoGel® 400 PHB |
110 - 150 µm |
0.4 - 0.6 mmol/g |
5g |
|
SP400 110150 130 |
HypoGel® 400 PHB |
110 - 150 µm |
0.4 - 0.6 mmol/g |
25g |
|
SP400 110150 130 |
HypoGel® 400 PHB |
110 - 150 µm |
0.4 - 0.6 mmol/g |
100g |
B7.5.2.5
Parahydroxybenzyl Alcohol Polystyrene Resins (PHB, Wang-type)
B7.5.2.5.1
Para Hydroxybenzyl Alcohol (PHB, Wang Linker ) on Ethylated Polystyrene Matrix
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 13 |
Polystyrene A PHB |
100 - 200 mesh |
0.5 - 1.0 mmol/g |
5g |
|
HA 1 100 13 |
Polystyrene A PHB |
100 - 200 mesh |
0.5 - 1.0 mmol/g |
25g |
|
HA 1 100 13 |
Polystyrene A PHB |
100 - 200 mesh |
0.5 - 1.0 mmol/g |
100g |
|
HA 1 400 13 |
Polystyrene A PHB |
200 - 400 mesh |
0.5 - 1.0 mmol/g |
5g |
|
HA 1 400 13 |
Polystyrene A PHB |
200 - 400 mesh |
0.5 - 1.0 mmol/g |
25g |
|
HA 1 400 13 |
Polystyrene A PHB |
200 - 400 mesh |
0.5 - 1.0 mmol/g |
100g |
|
HA 125160 13 |
Polystyrene A PHB |
125 - 160 µm |
0.5 - 1.0 mmol/g |
5g |
|
HA 125160 13 |
Polystyrene A PHB |
125 - 160 µm |
0.5 - 1.0 mmol/g |
25g |
|
HA 125160 13 |
Polystyrene A PHB |
125 - 160 µm |
0.5 - 1.0 mmol/g |
100g |
|
HA 160200 13 |
Polystyrene A PHB |
160 - 200 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 160200 13 |
Polystyrene A PHB |
160 - 200 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 160200 13 |
Polystyrene A PHB |
160 - 200 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 250315 13 |
Polystyrene A PHB |
250 - 315 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 250315 13 |
Polystyrene A PHB |
250 - 315 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 250315 13 |
Polystyrene A PHB |
250 - 315 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 400450 13 |
Polystyrene A PHB |
400 - 450 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 400450 13 |
Polystyrene A PHB |
400 - 450 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 400450 13 |
Polystyrene A PHB |
400 - 450 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 500560 13 |
Polystyrene A PHB |
500 - 560 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 500560 13 |
Polystyrene A PHB |
500 - 560 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 500560 13 |
Polystyrene A PHB |
500 - 560 µm |
0.5 - 0.8 mmol/g |
100g |
B7.5.2.5.2
Para Hydroxybenzyl Alcohol (PHB, Wang Linker) on Butylated Polystyrene Matrix
The linker is separated by a C4 spacer from the crosslinked matrix. Due to this spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HB 045080 13 |
Polystyrene C4 PHB |
45 - 80 µm |
0.8 - 1.2 mmol/g |
5g |
|
HB 045080 13 |
Polystyrene C4 PHB |
45 - 80 µm |
0.8 - 1.2 mmol/g |
25g |
|
HB 045080 13 |
Polystyrene C4 PHB |
45 - 80 µm |
0.8 - 1.2 mmol/g |
100g |
|
HB 080160 13 |
Polystyrene C4 PHB |
80 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
HB 080160 13 |
Polystyrene C4 PHB |
80 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
HB 080160 13 |
Polystyrene C4 PHB |
80 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
|
HB 125160 13 |
Polystyrene C4 PHB |
125 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
HB 125160 13 |
Polystyrene C4 PHB |
125 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
HB 125160 13 |
Polystyrene C4 PHB |
125 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
B7.5.2.5.3
Wang Resin - Para Hydroxybenzyl Alcohol (PHB) on Polystyrene
The Wang support is the most widely used resin for attaching carboxylic acids for further functionalisation. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH?CI? mixtures to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. Release of an amide function by treatment with an amine in the presence of a Lewis acid was also reported. Wang resin was used to add vinyl and iodobenzoic acids via carbodiimide coupling and the products subjected to Heck conditions with alkenes or with alkynes or to Suzuki coupling with boron reagents. The Ugi multicomponent condensation reaction was conducted on Wang resin with the carboxylic acid, amine or isonitrile as the anchored functional group. On a Wang resin primary, secondary, and tertiary alcohols have been converted to 4-methoxy-benzyl ethers. As well as anchoring carboxylic acids to this resin, phenols were attached under Mitsunobu conditions, subjected to further transformations and cleaved under acidic conditions.
Solid-phase lactam syntheses were also achieved by reaction of the resin-bound isonitrile with an amine and an w-keto-acid as well as other synthetic transformations such as the Biginelli reaction and construction of heterocycles such as quinolones, imidazoles, hydantoins, and 1,4-benzodiazepine-2,5-diones.
Literature
L 39
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 13 |
Polystyrene PHB (Wang resin) |
100 - 200 mesh |
0.8 - 1.25 mmol/g |
5g |
|
H 100 13 |
Polystyrene PHB (Wang resin) |
100 - 200 mesh |
0.8 - 1.25 mmol/g |
25g |
|
H 100 13 |
Polystyrene PHB (Wang resin) |
100 - 200 mesh |
0.8 - 1.25 mmol/g |
100g |
|
H 400 13 |
Polystyrene PHB (Wang resin) |
200 - 400 mesh |
0.8 - 1.25 mmol/g |
5g |
|
H 400 13 |
Polystyrene PHB (Wang resin) |
200 - 400 mesh |
0.8 - 1.25 mmol/g |
25g |
|
H 400 13 |
Polystyrene PHB (Wang resin) |
200 - 400 mesh |
0.8 - 1.25 mmol/g |
100g |
|
H 125160 13 |
Polystyrene PHB (Wang resin) |
125 - 160 µm |
0.8 - 1.25 mmol/g |
5g |
|
H 125160 13 |
Polystyrene PHB (Wang resin) |
125 - 160 µm |
0.8 - 1.25 mmol/g |
25g |
|
H 125160 13 |
Polystyrene PHB (Wang resin) |
125 - 160 µm |
0.8 - 1.25 mmol/g |
100g |
B7.5.3
Resins for Protected Peptide Amides
TOPPA - A Novel Resin for Synthesis of Protected Peptide Amides
This resin type is based on a TentaGel or polystyrene matrix and combines the very acid sensitive trityl handle with the acid sensitive Rink amide handle. The peptide synthesis can be performed by standard conditions. Treatment of the TOPPA resin with diluted AcOH, TFE or mixtures of both in dichloromethane cleaves the trityl ester bond and releases the total protected peptide amide (TOPPA). The C-terminus of the protected peptide amide is still masked by the Rink handle.
Literature
L 50
Please select a subcategory:
B7.5.3.1
Protected Amides from Polystyrene Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 75150.033023 |
PS TOPPA |
75 - 150 µm |
0.6 - 0.9 mmol/g |
1g |
|
H 75150.033023 |
PS TOPPA |
75 - 150 µm |
0.6 - 0.9 mmol/g |
5g |
|
H 75150.033023 |
PS TOPPA |
75 - 150 µm |
0.6 - 0.9 mmol/g |
25g |
B7.5.3.2
Protected Amides from TentaGel Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30902.012023 |
TentaGel® TOPPA |
90 µm |
0.18 - 0.25 mmol/g |
1g |
|
S 30902.012023 |
TentaGel® TOPPA |
90 µm |
0.18 - 0.25 mmol/g |
5g |
|
S 30902.012023 |
TentaGel® TOPPA |
90 µm |
0.18 - 0.25 mmol/g |
25g |
B7.5.4
Resins for the Synthesis of Thioesters
Trityl Mercapto Acetyl Leu PAM loaded to Aminomethyl Polystyrene
This resin can be used for the synthesis of peptide thioesters by Boc chemistry. After removal of the trityl protecting group by TFA/DCM treatment the first Boc amino acid is loaded to the resin by DIC/HOBt activation. Peptide synthesis follows the standard Boc synthesis protocol.
After finishing the peptide synthesis, the peptide thioester resin is treated by HF resulting in the deprotected peptide thioester derivative which can be used for native chemical ligation.
Literature
L 55
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 90 |
Polystyrene AM PAM Leu Acetyl Mercapto Trt |
100 - 200 mesh |
0.6 - 0.9 mmol/g |
1g |
|
H 100 90 |
Polystyrene AM PAM Leu Acetyl Mercapto Trt |
100 - 200 mesh |
0.6 - 0.9 mmol/g |
5g |
B7.5.5
Trityl Based Linkers
B7.5.5.1
Chloro-(2'-chloro)trityl Polystyrene Resins
A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. In particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides. Cleavage from this resin is achieved by using 1-95% TFA in CH?CI? (containing 8% triisopropylsilane), AcOH/CF?OH/CH?CI?, 0.5% TFA or hexafluoroisopropanol. Recently, this resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of b-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this condition.
Literature
L 37
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 33 |
Chloro-(2'-chloro)trityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 100 33 |
Chloro-(2'-chloro)trityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 100 33 |
Chloro-(2'-chloro)trityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 400 33 |
Chloro-(2'-chloro)trityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 400 33 |
Chloro-(2'-chloro)trityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 400 33 |
Chloro-(2'-chloro)trityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 125160 33 |
Chloro-(2'-chloro)trityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
5g |
|
H 125160 33 |
Chloro-(2'-chloro)trityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
25g |
|
H 125160 33 |
Chloro-(2'-chloro)trityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
100g |
|
H 160200 33 |
Chloro-(2'-chloro)trityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
5g |
|
H 160200 33 |
Chloro-(2'-chloro)trityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
25g |
|
H 160200 33 |
Chloro-(2'-chloro)trityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
100g |
|
H 250315 33 |
Chloro-(2'-chloro)trityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 250315 33 |
Chloro-(2'-chloro)trityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 250315 33 |
Chloro-(2'-chloro)trityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 400450 33 |
Chloro-(2'-chloro)trityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 400450 33 |
Chloro-(2'-chloro)trityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 400450 33 |
Chloro-(2'-chloro)trityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 500560 33 |
Chloro-(2'-chloro)trityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 500560 33 |
Chloro-(2'-chloro)trityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 500560 33 |
Chloro-(2'-chloro)trityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.5.5.2
Chlorotrityl Polystyrene Resins (Trityl Chloride Resin)
This highly acid labile resin is useful for the immobilization of alcohols, amines and carboxylic acids. Cleavage is in general achieved by using either 1-5 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis under basic acylation conditions. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Literature
L 36
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 31 |
Chlorotrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 100 31 |
Chlorotrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 100 31 |
Chlorotrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 400 31 |
Chlorotrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 400 31 |
Chlorotrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 400 31 |
Chlorotrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 125160 31 |
Chlorotrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
5g |
|
H 125160 31 |
Chlorotrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
25g |
|
H 125160 31 |
Chlorotrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
100g |
|
H 160200 31 |
Chlorotrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
5g |
|
H 160200 31 |
Chlorotrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
25g |
|
H 160200 31 |
Chlorotrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
100g |
|
H 250315 31 |
Chlorotrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 250315 31 |
Chlorotrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 250315 31 |
Chlorotrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 400450 31 |
Chlorotrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 400450 31 |
Chlorotrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 400450 31 |
Chlorotrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 500560 31 |
Chlorotrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 500560 31 |
Chlorotrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 500560 31 |
Chlorotrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.5.5.3
Hydroxytrityl Polystyrene Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 100 30 |
Hydroxytrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 100 30 |
Hydroxytrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 100 30 |
Hydroxytrityl Polystyrene |
100 - 200 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 400 30 |
Hydroxytrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
5g |
|
H 400 30 |
Hydroxytrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
25g |
|
H 400 30 |
Hydroxytrityl Polystyrene |
200 - 400 mesh |
0.8 - 1.5 mmol/g |
100g |
|
H 125160 30 |
Hydroxytrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
5g |
|
H 125160 30 |
Hydroxytrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
25g |
|
H 125160 30 |
Hydroxytrityl Polystyrene |
125 - 160 µm |
0.8 - 1.5 mmol/g |
100g |
|
H 160200 30 |
Hydroxytrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
5g |
|
H 160200 30 |
Hydroxytrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
25g |
|
H 160200 30 |
Hydroxytrityl Polystyrene |
160 - 200 µm |
0.8 - 1.3 mmol/g |
100g |
|
H 250315 30 |
Hydroxytrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 250315 30 |
Hydroxytrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 250315 30 |
Hydroxytrityl Polystyrene |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 400450 30 |
Hydroxytrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 400450 30 |
Hydroxytrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 400450 30 |
Hydroxytrityl Polystyrene |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 500560 30 |
Hydroxytrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 500560 30 |
Hydroxytrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 500560 30 |
Hydroxytrityl Polystyrene |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.5.5.4
Trityl Linker on Polar PEG Spacer Resins
B7.5.5.4.1
HypoGel® Resins with Trityl Linker
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. The hydrophilicity is between polystyrene and TentaGel® . Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
HypoGel® is a registered Trademark of Rapp Polymere GmbH
Literature: L 17
This very acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 120 |
HypoGel® 200 TRT-OH |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP200 110150 120 |
HypoGel® 200 TRT-OH |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP200 110150 120 |
HypoGel® 200 TRT-OH |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
|
SP400 110150 120 |
HypoGel® 400 TRT-OH |
110 - 150 µm |
0.4 - 0.6 mmol/g |
5g |
|
SP400 110150 120 |
HypoGel® 400 TRT-OH |
110 - 150 µm |
0.4 - 0.6 mmol/g |
25g |
|
SP400 110150 120 |
HypoGel® 400 TRT-OH |
110 - 150 µm |
0.4 - 0.6 mmol/g |
100g |
B7.5.5.4.2
TentaGel® Resins with Trityl Linker
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 4, L 5, L 6, L 7, L 24, L 25; see also: General Information
B7.5.5.4.2.1
TentaGel® HL TRT High Loaded TentaGel Resins with Hydroxytrityl Linker
This high loaded version of TentaGel® combines a significantly higher capacity with the advantages of
TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL12 012 |
TentaGel® HL TRT-OH |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL12 012 |
TentaGel® HL TRT-OH |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL12 012 |
TentaGel® HL TRT-OH |
75 µm |
0.3 - 0.4 mmol/g |
25g |
|
HL12 012 |
TentaGel® HL TRT-OH |
75 µm |
0.3 - 0.4 mmol/g |
50g |
B7.5.5.4.2.2
TentaGel® MB TRT TentaGel Macrobead Resins with Hydroxytrityl Linker
TentaGel® Macrobeads are highlighted by extraordinary large particle diameters and high capacities based on the TentaGel® technology and designed for single bead synthesis and single bead analysis.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 120 |
TentaGel® MB TRT-OH |
140 - 170 µm |
0.4 - 0.5 mmol/g |
1g |
|
MB 160 120 |
TentaGel® MB TRT-OH |
140 - 170 µm |
0.4 - 0.5 mmol/g |
5g |
|
MB 160 120 |
TentaGel® MB TRT-OH |
140 - 170 µm |
0.4 - 0.5 mmol/g |
25g |
|
MB 160 120 |
TentaGel® MB TRT-OH |
140 - 170 µm |
0.4 - 0.5 mmol/g |
50g |
|
MB 250 120 |
TentaGel® MB TRT-OH |
200 - 250 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 120 |
TentaGel® MB TRT-OH |
200 - 250 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 250 120 |
TentaGel® MB TRT-OH |
200 - 250 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 250 120 |
TentaGel® MB TRT-OH |
200 - 250 µm |
0.2 - 0.3 mmol/g |
50g |
|
MB 300 120 |
TentaGel® MB TRT-OH |
280 - 320 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 300 120 |
TentaGel® MB TRT-OH |
280 - 320 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 300 120 |
TentaGel® MB TRT-OH |
280 - 320 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 300 120 |
TentaGel® MB TRT-OH |
280 - 320 µm |
0.2 - 0.3 mmol/g |
50g |
B7.5.5.4.2.3
TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
TentaGel® R TRT Cl TentaGel Research Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
A special designed resin for research synthesis. This resin is recommended for long peptide sequences (up to 100 residues) and difficult sequences. The resin shows an increased swelling volume and a significant lower loading.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions. The sensitivity toward acid treatment is comparable to the 2-CTC linker.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
R 28 031 |
TentaGel® R TRT-Cl |
90 µm |
0.15 - 0.22 mmol/g |
5g |
|
R 28 031 |
TentaGel® R TRT-Cl |
90 µm |
0.15 - 0.22 mmol/g |
25g |
|
R 28 031 |
TentaGel® R TRT-Cl |
90 µm |
0.15 - 0.22 mmol/g |
50g |
B7.5.5.4.2.4
TentaGel® S TRT Standard TentaGel Resins with Hydroxytrityl Linker
Standard resin for a large number of applications, useful in batch and flow through systems.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 012 |
TentaGel® S TRT-OH |
90 µm |
0.2 - 0.28 mmol/g |
1g |
|
S 30 012 |
TentaGel® S TRT-OH |
90 µm |
0.2 - 0.28 mmol/g |
5g |
|
S 30 012 |
TentaGel® S TRT-OH |
90 µm |
0.2 - 0.28 mmol/g |
25g |
|
S 30 012 |
TentaGel® S TRT-OH |
90 µm |
0.2 - 0.28 mmol/g |
50g |
B7.5.5.4.2.5
TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
TentaGel® S TRT Cl Standard TentaGel Resins with Chlorotrityl Linker
This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel resins, the resin should be used immediately.
Standard resin for a large number of applications, useful in batch and flow through systems.
This resin is recommended for synthesis of standard peptides up to 40 residues in length.
This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50 % TFA in CH?Cl? (containing 5 % triisopropylsilane) or acetic acid.
This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.
Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
Literature
L 14
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 031 |
TentaGel® S TRT-Cl |
90 µm |
0.2 - 0.3 mmol/g |
5g |
|
S 30 031 |
TentaGel® S TRT-Cl |
90 µm |
0.2 - 0.3 mmol/g |
25g |
|
S 30 031 |
TentaGel® S TRT-Cl |
90 µm |
0.2 - 0.3 mmol/g |
50g |
B7.6.1
Polar PEG Spacer Resins with Aromatic Formyl Linker
B7.6.1.1
4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
4-Formyl Phenoxy on HypoGel Resins ( FP-linker)
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
L 30, L 31
Due to the lack of amide bonds and of benzylic linkages as well as the very good swelling properties in a broad variety of solvents this resin is well suited for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L17
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 170 |
HypoGel® 200 FP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
5g |
|
SP200 110150 170 |
HypoGel® 200 FP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
25g |
|
SP200 110150 170 |
HypoGel® 200 FP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
100g |
|
SP400 110150 170 |
HypoGel® 400 FP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
5g |
|
SP400 110150 170 |
HypoGel® 400 FP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
25g |
|
SP400 110150 170 |
HypoGel® 400 FP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
100g |
B7.6.1.2
4-Formyl-3-Methoxy Phenoxy on HypoGel Resins ( FMP-linker)
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 160 |
HypoGel® 200 FMP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
5g |
|
SP200 110150 160 |
HypoGel® 200 FMP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
25g |
|
SP200 110150 160 |
HypoGel® 200 FMP |
110 - 150 µm |
0.5 - 0.7 mmol/g |
100g |
|
SP400 110150 160 |
HypoGel® 400 FMP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
5g |
|
SP400 110150 160 |
HypoGel® 400 FMP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
25g |
|
SP400 110150 160 |
HypoGel® 400 FMP |
110 - 150 µm |
0.4 - 0.6 mmol/g |
100g |
B7.6.1.3
4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
4-Formyl-3-Methoxy Phenoxy on TentaGel Resins ( FMP-linker)
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. The PEG spacer is attached to the matrix via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. As PEG is a "chameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix). These graft copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da.
Due to the lack of amide bonds and of benzylic linkages as well as the excellent swelling properties in a great variety of solvents this resin is ideal for solid phase syntheses of secondary sulfonamides and carboxamides.
Literature
L 4, L 5, L 6, L 7, L 24, L 25, L 31; see also: General Information
B7.6.1.3.1
TentaGel® HL FMP High Loaded TentaGel Resins Modified with FMP Linker
This highloaded version of TentaGel® combines a significantly higher capacity with the advantages of TentaGel® resins. The spacer is in the range of MW 1500 - 2000 Da.
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 016 |
TentaGel® HL FMP |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL 12 016 |
TentaGel® HL FMP |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL 12 016 |
TentaGel® HL FMP |
75 µm |
0.3 - 0.4 mmol/g |
25g |
|
HL 12 016 |
TentaGel® HL FMP |
75 µm |
0.3 - 0.4 mmol/g |
100g |
B7.6.1.3.2
TentaGel® MB FMP TentaGel Macrobeads Modified with FMP Linker
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 160 |
TentaGel® MB FMP |
140 - 170 µm |
0.35 - 0.45 |
1g |
|
MB 160 160 |
TentaGel® MB FMP |
140 - 170 µm |
0.35 - 0.45 |
5g |
|
MB 160 160 |
TentaGel® MB FMP |
140 - 170 µm |
0.35 - 0.45 |
25g |
|
MB 160 160 |
TentaGel® MB FMP |
140 - 170 µm |
0.35 - 0.45 |
100g |
|
MB 250 160 |
TentaGel® MB FMP |
200 - 250 µm |
0.2 - 0.3 |
1g |
|
MB 250 160 |
TentaGel® MB FMP |
200 - 250 µm |
0.2 - 0.3 |
5g |
|
MB 250 160 |
TentaGel® MB FMP |
200 - 250 µm |
0.2 - 0.3 |
25g |
|
MB 250 160 |
TentaGel® MB FMP |
200 - 250 µm |
0.2 - 0.3 |
100g |
|
MB 300 160 |
TentaGel® MB FMP |
280 - 320 µm |
0.2 - 0.3 |
1g |
|
MB 300 160 |
TentaGel® MB FMP |
280 - 320 µm |
0.2 - 0.3 |
5g |
|
MB 300 160 |
TentaGel® MB FMP |
280 - 320 µm |
0.2 - 0.3 |
25g |
|
MB 300 160 |
TentaGel® MB FMP |
280 - 320 µm |
0.2 - 0.3 |
100g |
B7.6.1.3.3
TentaGel® S FMP Standard TentaGel Resins Modified with FMP Linker
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 016 |
TentaGel® S FMP |
90 µm |
0.2 - 0.25 |
1g |
|
S 30 016 |
TentaGel® S FMP |
90 µm |
0.2 - 0.25 |
5g |
|
S 30 016 |
TentaGel® S FMP |
90 µm |
0.2 - 0.25 |
25g |
|
S 30 016 |
TentaGel® S FMP |
90 µm |
0.2 - 0.25 |
100g |
B7.6.2
Polystyrene based Resins
B7.6.2.1
4-Formyl Phenoxyethyl Polystyrene Resins (FP-Linker, 4-Alkoxybenzaldehyd resin)
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 07 |
Polystyrene A FP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
5g |
|
HA 1 100 07 |
Polystyrene A FP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
25g |
|
HA 1 100 07 |
Polystyrene A FP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
100g |
|
HA 1 400 07 |
Polystyrene A FP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
5g |
|
HA 1 400 07 |
Polystyrene A FP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
25g |
|
HA 1 400 07 |
Polystyrene A FP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
100g |
|
HA 125160 07 |
Polystyrene A FP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
5g |
|
HA 125160 07 |
Polystyrene A FP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
25g |
|
HA 125160 07 |
Polystyrene A FP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
100g |
|
HA 160200 07 |
Polystyrene A FP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
5g |
|
HA 160200 07 |
Polystyrene A FP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
25g |
|
HA 160200 07 |
Polystyrene A FP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
100g |
|
HA 250315 07 |
Polystyrene A FP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 250315 07 |
Polystyrene A FP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 250315 07 |
Polystyrene A FP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 400450 07 |
Polystyrene A FP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 400450 07 |
Polystyrene A FP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 400450 07 |
Polystyrene A FP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 500560 07 |
Polystyrene A FP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 500560 07 |
Polystyrene A FP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 500560 07 |
Polystyrene A FP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
100g |
B7.6.2.2
4-Formyl-3-Methoxy Phenoxybutyl Polystyrene Resins (FMP-Linker)
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HB 045080 08 |
Polystyrene C4 FMP |
45 - 80 µm |
0.7 - 1.0 mmol/g |
5g |
|
HB 045080 08 |
Polystyrene C4 FMP |
45 - 80 µm |
0.7 - 1.0 mmol/g |
25g |
|
HB 045080 08 |
Polystyrene C4 FMP |
45 - 80 µm |
0.7 - 1.0 mmol/g |
100g |
|
HB 080160 08 |
Polystyrene C4 FMP |
80 - 160 µm |
0.7 - 1.0 mmol/g |
5g |
|
HB 080160 08 |
Polystyrene C4 FMP |
80 - 160 µm |
0.7 - 1.0 mmol/g |
25g |
|
HB 080160 08 |
Polystyrene C4 FMP |
80 - 160 µm |
0.7 - 1.0 mmol/g |
100g |
|
HB 125160 08 |
Polystyrene C4 FMP |
125 - 160 µm |
0.7 - 1.0 mmol/g |
5g |
|
HB 125160 08 |
Polystyrene C4 FMP |
125 - 160 µm |
0.7 - 1.0 mmol/g |
25g |
|
HB 125160 08 |
Polystyrene C4 FMP |
125 - 160 µm |
0.7 - 1.0 mmol/g |
100g |
B7.6.2.3
4-Formyl-3-Methoxy Phenoxyethyl Polystyrene Resins (FMP-Linker)
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 08 |
Polystyrene A FMP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
5g |
|
HA 1 100 08 |
Polystyrene A FMP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
25g |
|
HA 1 100 08 |
Polystyrene A FMP |
100 - 200 mesh |
0.7 - 1.1 mmol/g |
100g |
|
HA 1 400 08 |
Polystyrene A FMP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
5g |
|
HA 1 400 08 |
Polystyrene A FMP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
25g |
|
HA 1 400 08 |
Polystyrene A FMP |
200 - 400 mesh |
0.7 - 1.1 mmol/g |
100g |
|
HA 125160 08 |
Polystyrene A FMP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
5g |
|
HA 125160 08 |
Polystyrene A FMP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
25g |
|
HA 125160 08 |
Polystyrene A FMP |
125 - 160 µm |
0.7 - 1.1 mmol/g |
100g |
|
HA 160200 08 |
Polystyrene A FMP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
5g |
|
HA 160200 08 |
Polystyrene A FMP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
25g |
|
HA 160200 08 |
Polystyrene A FMP |
160 - 200 µm |
0.7 - 1.1 mmol/g |
100g |
|
HA 250315 08 |
Polystyrene A FMP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 250315 08 |
Polystyrene A FMP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 250315 08 |
Polystyrene A FMP |
250 - 315 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 400450 08 |
Polystyrene A FMP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 400450 08 |
Polystyrene A FMP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 400450 08 |
Polystyrene A FMP |
400 - 450 µm |
0.5 - 0.8 mmol/g |
100g |
|
HA 500560 08 |
Polystyrene A FMP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
5g |
|
HA 500560 08 |
Polystyrene A FMP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
25g |
|
HA 500560 08 |
Polystyrene A FMP |
500 - 560 µm |
0.5 - 0.8 mmol/g |
100g |
B7.7.1
Polar PEG Spacer Resins with Base Labile Linkers
B7.7.1.1
4-(Hydroxymethyl) Benzoic Acid (HMBA) on HypoGel® Resins
HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.
These resins show high loading and a hydrophilicity between polystyrene and TentaGel®
This resin is derived from HypoGel® amine and the base labile 4-(hydroxymethyl)benzoic acid linker. It is a versatile support for the immobilization of carboxylic acids. The resulting ester bond is stable to strong acids but is cleaved by nucleophiles like amines, hydrazine or alkoxides.
Literature
L 17
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 140 |
HypoGel® 200 HMBA |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP200 110150 140 |
HypoGel® 200 HMBA |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP200 110150 140 |
HypoGel® 200 HMBA |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
|
SP400 110150 140 |
HypoGel® 400 HMBA |
110 - 150 µm |
0.4 - 0.6 mmol/g |
5g |
|
SP400 110150 140 |
HypoGel® 400 HMBA |
110 - 150 µm |
0.4 - 0.6 mmol/g |
25g |
|
SP400 110150 140 |
HypoGel® 400 HMBA |
110 - 150 µm |
0.4 - 0.6 mmol/g |
100g |
B7.7.1.2
4-(Hydroxymethyl) Benzoic Acid (HMBA) on TentaGel® Resins
B7.7.1.2.1
TentaGel® HL HMBA HMBA Linker Attached to High Loaded TentaGel Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL12 014 |
TentaGel® HL HMBA |
75 µm |
0.3 - 0.4 mmol/g |
1g |
|
HL12 014 |
TentaGel® HL HMBA |
75 µm |
0.3 - 0.4 mmol/g |
5g |
|
HL12 014 |
TentaGel® HL HMBA |
75 µm |
0.3 - 0.4 mmol/g |
25g |
|
HL12 014 |
TentaGel® HL HMBA |
75 µm |
0.3 - 0.4 mmol/g |
50g |
B7.7.1.2.2
TentaGel® MB HMBA HMBA Linker Attached to TentaGel Macrobeads
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
MB 160 140 |
TentaGel® MB HMBA |
140 - 170 µm |
0.4 - 0.5 mmol/g |
1g |
|
MB 160 140 |
TentaGel® MB HMBA |
140 - 170 µm |
0.4 - 0.5 mmol/g |
5g |
|
MB 160 140 |
TentaGel® MB HMBA |
140 - 170 µm |
0.4 - 0.5 mmol/g |
25g |
|
MB 160 140 |
TentaGel® MB HMBA |
140 - 170 µm |
0.4 - 0.5 mmol/g |
50g |
|
MB 250 140 |
TentaGel® MB HMBA |
200 - 250 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 250 140 |
TentaGel® MB HMBA |
200 - 250 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 250 140 |
TentaGel® MB HMBA |
200 - 250 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 250 140 |
TentaGel® MB HMBA |
200 - 250 µm |
0.2 - 0.3 mmol/g |
50g |
|
MB 300 140 |
TentaGel® MB HMBA |
280 - 320 µm |
0.2 - 0.3 mmol/g |
1g |
|
MB 300 140 |
TentaGel® MB HMBA |
280 - 320 µm |
0.2 - 0.3 mmol/g |
5g |
|
MB 300 140 |
TentaGel® MB HMBA |
280 - 320 µm |
0.2 - 0.3 mmol/g |
25g |
|
MB 300 140 |
TentaGel® MB HMBA |
280 - 320 µm |
0.2 - 0.3 mmol/g |
50g |
B7.7.1.2.3
TentaGel® R HMBA HMBA Linker Attached to TentaGel Research Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
R 28 023 |
TentaGel® R HMBA |
90 µm |
0.18 - 0.22 mmol/g |
1g |
|
R 28 023 |
TentaGel® R HMBA |
90 µm |
0.18 - 0.22 mmol/g |
5g |
|
R 28 023 |
TentaGel® R HMBA |
90 µm |
0.18 - 0.22 mmol/g |
25g |
|
R 28 023 |
TentaGel® R HMBA |
90 µm |
0.18 - 0.22 mmol/g |
50g |
B7.7.1.2.4
TentaGel® S HMBA HMBA Linker Attached to Standard TentaGel Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
S 30 014 |
TentaGel® S HMBA |
90 µm |
0.2 - 0.28 mmol/g |
1g |
|
S 30 014 |
TentaGel® S HMBA |
90 µm |
0.2 - 0.28 mmol/g |
5g |
|
S 30 014 |
TentaGel® S HMBA |
90 µm |
0.2 - 0.28 mmol/g |
25g |
|
S 30 014 |
TentaGel® S HMBA |
90 µm |
0.2 - 0.28 mmol/g |
50g |
B7.7.2
Polystyrene Resins with Base Labile Linkers
B7.7.2.1
4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminoethyl Polystyrene
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HA 1 100 14 |
Polystyrene A HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
5g |
|
HA 1 100 14 |
Polystyrene A HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
25g |
|
HA 1 100 14 |
Polystyrene A HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
100g |
|
HA 1 400 14 |
Polystyrene A HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
5g |
|
HA 1 400 14 |
Polystyrene A HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
25g |
|
HA 1 400 14 |
Polystyrene A HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
100g |
|
HA 125160 14 |
Polystyrene A HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
HA 125160 14 |
Polystyrene A HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
HA 125160 14 |
Polystyrene A HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
|
HA 160200 14 |
Polystyrene A HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
5g |
|
HA 160200 14 |
Polystyrene A HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
25g |
|
HA 160200 14 |
Polystyrene A HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
100g |
|
HA 250315 14 |
Polystyrene A HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 250315 14 |
Polystyrene A HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 250315 14 |
Polystyrene A HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
HA 400450 14 |
Polystyrene A HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 400450 14 |
Polystyrene A HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 400450 14 |
Polystyrene A HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
HA 500560 14 |
Polystyrene A HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
HA 500560 14 |
Polystyrene A HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
HA 500560 14 |
Polystyrene A HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B7.7.2.2
4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminomethyl Polystyrene
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
H 1 100 14 |
Polystyrene AM HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 1 100 14 |
Polystyrene AM HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
25g |
|
H 1 100 14 |
Polystyrene AM HMBA |
100 - 200 mesh |
0.8 - 1.2 mmol/g |
100g |
|
H 1 400 14 |
Polystyrene AM HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
5g |
|
H 1 400 14 |
Polystyrene AM HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
25g |
|
H 1 400 14 |
Polystyrene AM HMBA |
200 - 400 mesh |
0.8 - 1.2 mmol/g |
100g |
|
H 125160 14 |
Polystyrene AM HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
5g |
|
H 125160 14 |
Polystyrene AM HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
25g |
|
H 125160 14 |
Polystyrene AM HMBA |
125 - 160 µm |
0.8 - 1.2 mmol/g |
100g |
|
H 160200 14 |
Polystyrene AM HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
5g |
|
H 160200 14 |
Polystyrene AM HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
25g |
|
H 160200 14 |
Polystyrene AM HMBA |
160 - 200 µm |
0.8 - 1.2 mmol/g |
100g |
|
H 250315 14 |
Polystyrene AM HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 250315 14 |
Polystyrene AM HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 250315 14 |
Polystyrene AM HMBA |
250 - 315 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 400450 14 |
Polystyrene AM HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 400450 14 |
Polystyrene AM HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 400450 14 |
Polystyrene AM HMBA |
400 - 450 µm |
0.6 - 1.0 mmol/g |
100g |
|
H 500560 14 |
Polystyrene AM HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
5g |
|
H 500560 14 |
Polystyrene AM HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
25g |
|
H 500560 14 |
Polystyrene AM HMBA |
500 - 560 µm |
0.6 - 1.0 mmol/g |
100g |
B8.1.1
Bromo Acetal Resins
B8.1.1.1
Bromoacetal Linker on HypoGel® Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
5g |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
25g |
|
SP200 110150 190 |
HypoGel® 200 Bromo Acetal |
110 - 150 µm |
0.75 - 0.95 mmol/g |
100g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
5g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
25g |
|
SP400 110150 190 |
HypoGel® 400 Bromo Acetal |
110 - 150 µm |
0.6 - 0.8 mmol/g |
100g |
B8.1.1.2
Bromoacetal Linker on TentaGel® Resins
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
5g |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
25g |
|
HL 12 019 |
TentaGel® HL Bromo Acetal |
75 µm |
0.4 - 0.55 mmol/g |
100g |
B8.1.2
Diol Resins
B8.1.2.1
HypoGel® Diol
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
5g |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
25g |
|
SP200 110150 10 |
HypoGel® 200 Diol |
110 - 150 µm |
1.2 - 1.5 mmol/g |
100g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
5g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
25g |
|
SP400 110150 10 |
HypoGel® 400 Diol |
110 - 150 µm |
0.9 - 1.3 mmol/g |
100g |
B8.1.2.2
TentaGel® Diol
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HL 12 01 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
5g |
|
HL 12 01 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
25g |
|
HL 12 01 |
TentaGel® HL Diol |
75 µm |
0.6 - 0.8 mmol/g |
100g |
|
貨號(hào) |
名稱(chēng) |
capacity |
包裝 |
|
SC11011 |
ScavengePore® Benzenesulfonic acid, Na+-form |
1 - 2 mmol/g |
10g |
|
SC11011 |
ScavengePore® Benzenesulfonic acid, Na+-form |
1 - 2 mmol/g |
100g |
|
SC11012 |
ScavengePore® Benzyltriethylammonium chloride |
0.5 - 1 mmol/g |
10g |
|
SC11012 |
ScavengePore® Benzyltriethylammonium chloride |
0.5 - 1 mmol/g |
100g |
|
SC11013 |
ScavengePore® Benzoic Acid |
0.5 - 2.0 mmol/g |
5g |
|
SC11013 |
ScavengePore® Benzoic Acid |
0.5 - 2.0 mmol/g |
25g |
|
SC11014 |
ScavengePore® Benzenesulfonic acid, H+-form |
1 - 2 mmol/g |
10g |
|
SC11014 |
ScavengePore® Benzenesulfonic acid, H+-form |
1 - 2 mmol/g |
100g |
|
SC11102 |
ScavengePore® Benzylamine |
0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g |
5g |
|
SC11102 |
ScavengePore® Benzylamine |
0.5 - 1.5 mmol/g and 2 - 3.5 mmol/g |
25g |
|
SC11103 |
ScavengePore® Benzyl Isocyanate |
0.5 - 1.1 mmol/g |
5g |
|
SC11103 |
ScavengePore® Benzyl Isocyanate |
0.5 - 1.1 mmol/g |
25g |
|
SC11207 |
ScavengePore® 4-Phenethyloxybenzaldehyde |
0.5 - 1.2 mmol/g |
5g |
|
SC11207 |
ScavengePore® 4-Phenethyloxybenzaldehyde |
0.5 - 1.2 mmol/g |
25g |
|
SC11208 |
ScavengePore® Phenethyldiethylamine |
0.5 - 1.5 mmol/g |
5g |
|
SC11208 |
ScavengePore® Phenethyldiethylamine |
0.5 - 1.5 mmol/g |
25g |
|
SC11209 |
ScavengePore® Phenethylmorpholine |
0.5 - 1.2 mmol/g |
5g |
|
SC11209 |
ScavengePore® Phenethylmorpholine |
0.5 - 1.2 mmol/g |
25g |
|
SC11210 |
ScavengePore® Phenethylpiperidine |
0.5 - 1.2 mmol/g |
5g |
|
SC11210 |
ScavengePore® Phenethylpiperidine |
0.5 - 1.2 mmol/g |
25g |
B8.3.1
Polymer Supported Palladium
|
貨號(hào) |
名稱(chēng) |
capacity |
包裝 |
|
HR 100 31-Pd |
Polystyrene-Tetrakis (Triphenylphosphine) Palladium |
100 - 200 mesh |
1g |
|
HR 100 31-Pd |
Polystyrene-Tetrakis (Triphenylphosphine) Palladium |
100 - 200 mesh |
5g |
B8.3.2
Polystyrene Triphenylphosphine
|
貨號(hào) |
名稱(chēng) |
particle size |
capacity |
包裝 |
|
HR 100 31-0 |
Polystyrene-Triphenylphosphine |
100 - 200 mesh |
1 - 1.5 mmol/g |
5g |
|
HR 100 31-0 |
Polystyrene-Triphenylphosphine |
100 - 200 mesh |
1 - 1.5 mmol/g |
25g |
|
HR 100 31-0 |
Polystyrene-Triphenylphosphine |
100 - 200 mesh |
1 - 1.5 mmol/g |
100g |
|
HR 400 31-0 |
Polystyrene-Triphenylphosphine |
200 - 400 mesh |
1 - 1.5 mmol/g |
5g |
|
HR 400 31-0 |
Polystyrene-Triphenylphosphine |
200 - 400 mesh |
1 - 1.5 mmol/g |
25g |
|
HR 400 31-0 |
Polystyrene-Triphenylphosphine |
200 - 400 mesh |
1 - 1.5 mmol/g |
100g |
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